Probing an unusual carbon-carbon bond cleavage using experimental and computational approaches

POLITANO, FABRIZIO; URANGA, JORGE G.; BUJÁN, ELBA I.; LEADBEATER, NICHOLAS E.

New London

Simposio; 2nd annual ACS-CVS (Connecticut Valley Section) Symposium on Applied Synthesis; 2018

ACS-CVS

Experimental and computational studies have been performed in order to explain an unusual carbon-carbon bond cleavage that occurs in the preparation of certain benzimidazole N-oxides. The results of our studies have allowed us to understand the factors determining the observed fragmentation and we will present our results here.